单位所在地区:其它地区-其它地区 | 单位行业:高校/科研机构 | 单位规模:10000人以上
Our interdisciplinary research groups work on complex regulations of actin remodeling during signal transduction under physiological and pathological conditions. We study molecular mechanisms by which biomolecular phase separation finetunes physical-chemical properties of the macromolecular complex to reorganize actin polymerization by tuning the biochemical activities in the membrane-associated membrane-less organelles. We also focus on the mechanisms of mechanosensing and mechanotransduction, by which cell wall (CW) – plasma membrane (PM) – actin cytoskeleton (AC) continuum regulates molecular dynamics and functions of the integrated biomolecules through tunning their molecular condensation and thereby modulates cellular signal transductions.